How Buprenorphine Works as an Opioid Use Disorder (OUD) Treatment?

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As a partial opioid agonist, buprenorphine reduces cravings and withdrawal by partially activating opioid receptors in the brain, but has a “ceiling effect” that lowers euphoria and respiratory depression risk compared to drugs like heroin.

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This makes buprenorphine a safer option than full agonists like methadone. Buprenorphine also has a long duration of action, allowing for alternate-day dosing.

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Effectiveness of Buprenorphine Treatment

Buprenorphine decreased opioid use and increased treatment retention in placebo-controlled clinical trials. 

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Patients who received buprenorphine are 38% less likely to die from opioid overdose than those not on medication.

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Effectiveness of Buprenorphine Treatment

Buprenorphine is most effective as part of a “whole-patient” approach with behavioral counseling and support services. PCPs can provide this directly or via referral.

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At Nirvana Recovery Arizona, we can fight the opioid crisis problem thorugh

Drug and Alcohol Rehab Arizona

Intensive Outpatient Program

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Aftercare Support

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